email: rreggiar <@> stanford [dot] edu

updates

2023-08 – Finally, the main focus of my PhD is published in Nature Biomedical Engineering: The reveal of our repeat-aware approach to RNA liquid biopsy.

2023-08 – I’m now staring my K00-funded postdoctoral appointment at Stanford University with Howard Y. Chang!!

2022-08 – I just wrapped up teaching the 2022 UCSC Genomics Institute Summer Short Course in Bioinformatics, check out the course material and website here.
- I managed another instance of this class in the summer of 2023, the link is updated with info from that session

2022-07 – Our work on mutant KRAS-driven epigenomic changes in early tumorigenesis is out now published in Cell Reports!

featured

• Featured in NIH Director’s blog: New Approach to ‘Liquid Biopsy’ Relies on Repetitive RNA in the Bloodstream

• New blood test for noncoding RNA significantly improves cancer detection

• STUDY VALIDATING CLEARNOTE HEALTH’S AVANTECT PANCREATIC CANCER DETECTION TEST PUBLISHED IN THE JOURNAL CLINICAL GASTROENTEROLOGY AND HEPATOLOGY

• Closing cell—and academic—gaps

• Hallmark cancer gene regulates RNA ‘dark matter’

works

Reggiardo, Roman E., Sreelakshmi Velandi Maroli, Vikas Peddu, et al. “Profiling of Repetitive RNA Sequences in the Blood Plasma of Patients with Cancer.” Nature Biomedical Engineering, Aug. 2023, https://doi.org/10.1038/s41551-023-01081-7.

Martin, Eric W., et al. “Dynamics of Chromatin Accessibility During Hematopoietic Stem Cell Differentiation Into Progressively Lineage-Committed Progeny.” Stem Cells, vol. 41, no. 5, May 2023, pp. 520–39, https://doi.org/10.1093/stmcls/sxad022.

Haan, David, et al. “Epigenomic Blood-Based Early Detection of Pancreatic Cancer Employing Cell-Free DNA.” Clinical Gastroenterology and Hepatology: The Official Clinical Practice Journal of the American Gastroenterological Association, Mar. 2023, pp. S1542-3565(23)00224-0, https://doi.org/10.1016/j.cgh.2023.03.016.

Reggiardo, Roman E., Sreelakshmi Velandi Maroli, Haley Halasz, et al. “Mutant KRAS Regulates Transposable Element RNA and Innate Immunity via KRAB Zinc-Finger Genes.” Cell Reports, vol. 40, no. 3, July 2022, p. 111104, https://doi.org/10.1016/j.celrep.2022.111104.

Khojah, Reem, et al. Extracellular RNA Signatures of Mutant KRAS(G12C) Lung Adenocarcinoma Cells. Preprint, Genomics, Feb. 2022, https://doi.org/10.1101/2022.02.23.481574.

Reggiardo, Roman E., Sreelakshmi Velandi Maroli, and Daniel H. Kim. “LncRNA Biomarkers of Inflammation and Cancer.” Long Noncoding RNA, edited by Susan Carpenter, vol. 1363, Springer International Publishing, 2022, pp. 121–45, https://doi.org/10.1007/978-3-030-92034-0_7.

Martin, Eric W., et al. “Chromatin Accessibility Maps Provide Evidence of Multilineage Gene Priming in Hematopoietic Stem Cells.” Epigenetics & Chromatin, vol. 14, no. 1, Dec. 2021, p. 2, https://doi.org/10.1186/s13072-020-00377-1.

Anderson, Erica J. P., et al. “Late Onset Obesity in Mice with Targeted Deletion of Potassium Inward Rectifier Kir7.1 from Cells Expressing the Melanocortin-4 Receptor.” Journal of Neuroendocrinology, vol. 31, no. 1, Jan. 2019, p. e12670, https://doi.org/10.1111/jne.12670.